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컨퍼런스 커버리지

American Association for Cancer Research (AACR) Annual Meeting 2025

25 Aprill - 30 Aprill, 2025, United States

First-line penpulimab plus chemo offers survival benefits for R/M nasopharyngeal carcinoma

2025-08-07

The use of penpulimab, in combination with gemcitabine and cisplatin or carboplatin, as first-line treatment for recurrent or metastatic (R/M) nasopharyngeal carcinoma (NPC) provides statistically significant and clinically meaningful benefit, according to a study presented at AACR 2025.
Nurulimab-prolgolimab superior to prolgolimab alone in metastatic melanoma

2025-08-07

First-line nurulimab and prolgolimab combination therapy demonstrated superior efficacy compared with prolgolimab monotherapy in patients with unresectable or metastatic melanoma, according to the OCTAVA trial presented at AACR 2025.
Perioperative pembrolizumab may shift treatment paradigm in resectable HNSCC

2025-08-07

In the first interim analysis of the phase III KEYNOTE-689 trial, pembrolizumab improves event-free survival (EFS) and major pathological response (mPR) rate, independent of CPS*, when added to standard-of-care (SoC) treatment for resectable locally advanced head and neck squamous cell carcinoma (LA HNSCC).
Topical BRAF inhibitor relieves EGFR-induced acneiform eruption

2025-08-07

LUT014 gel, a novel, small-molecule, topical formulation of a BRAF inhibitor, relieves acneiform rash toxicities from anti-EGFR therapies, findings from a phase II study suggest.
Zongertinib shows antitumour activity in previously treated HER2-mutant NSCLC

2025-08-07

The oral, irreversible, HER2-selective tyrosine kinase inhibitor (TKI) zongertinib confers clinically meaningful benefit to patients with previously treated HER2-mutant nonsmall cell lung cancer (NSCLC), including those with brain metastases, while having a manageable safety profile, according to the phase 1A/1B Beamion LUNG-1 trial.

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